Initially, the chromosome was synthesized in segments called megachunks, which were then cloned into vectors and integrated into yeast strains through homologous recombination. Each megachunk ...

To tackle the conundrum, Yingjin Yuan, a professor of biochemical engineering at Tianjin University, turned to deoxyribonucleic acid (DNA) and has designed yeast artificial chromosomes as a ...

Instead of the linear chromosomes found in mammals, the team crafted a circular chromosome, which is compatible with DNA replication in yeast. They then assembled the HAC inside budding yeast. By ...

Fission yeast and budding yeast are free-living haploid cells that are easily grown in the laboratory. They have different cell shapes and patterns of division. Left, fission yeast; right ...

Scientists have engineered a chromosome entirely from scratch that will contribute to the production of the world’s first synthetic yeast. Researchers in the Manchester Institute of Biotechnology (MIB ...

Researchers have generated a full-length clone of the novel coronavirus genome using artificial chromosomes in brewers’ yeast, according to a paper published in Nature on Monday (May 4). While other ...