The allele frequency represents the incidence of a gene variant in a population. Alleles are variant forms of a gene that are located at the same position, or genetic locus, on a chromosome.

New findings suggest that reducing the variant allele frequency of JAK2V617F should be a goal of treatment for polycythemia ...

Allele frequencies have long been studied by biologists interested in evolution and speciation. More recently, with the application of molecular markers in human DNA profiling we have also seen ...

BACKGROUND: Desmosomal gene variants (DGVs) have been associated with a diverse spectrum of phenotypic manifestations within ...

Highly sensitive and accurate methods are needed to define target allele frequencies (AFs) in next-generation sequencing (NGS) reference material which is critical for the development and ...

With this tool, the user can get information about the county-specific frequencies of alleles that are present in the FINRISK data set. Depending on the rarity of the allele, the tool shows either the ...

A coalition of 13 leading life science and diagnostics organizations today announced the formation of the Allele Frequency Community, a landmark initiative that is creating an extensive, high-quality ...

Researchers used field data from 2012 to 2015 to study mortality and allele frequency changes in the sea star Pisaster ochraceus during a mass mortality event in north central California ...

Age-related germline landscape of endometrial cancer: Focus on early-onset cases. Estimated prevalence of pathogenic variants in patients with breast, colon, and/or endometrial cancer who do not meet ...

Clinical, Genomic, and Transcriptomic Data Profiling of Biliary Tract Cancer Reveals Subtype-Specific Immune Signatures The ideas and opinions expressed in this Data Supplement do not necessarily ...