This article reviews the published literature on the use of venlafaxine, fluoxetine, and paroxetine for the treatment of hot flashes.

Anecdotal evidence suggested that venlafaxine, one of a newer class of antidepressants called selective norepinephrine reuptake inhibitors, could alleviate hot flashes, he explained. A four-week ...

The analysis by Loprinzi and co-workers supports the notion that antidepressants and gabapentin decrease menopausal hot flashes. In addition, the study showed that venlafaxine and paroxetine were ...

In one trial, women treated unsuccessfully with the serotonin–norepinephrine reuptake inhibitor venlafaxine, were crossed over to citalopram therapy, and hot flashes were reduced by 50%.