Regeneron's work led to the creation of the VelocImmune mouse. The VelocImmune mouse makes part-human and part-mouse antibodies, which allows the VelocImmune mouse to mount a healthy, functional and ...

Novel in vivo platforms, such as Regeneron's VelocImmune mouse that produced dupilumab, have an edge over those that went before—they produce fully human antibodies while retaining an intact ...

The VelocImmune mouse, which UT Southwestern researchers will use, unlike other human-antibody-producing mice, mounts a robust immune response that is virtually indistinguishable from that of a ...

Immunogenicity led to the discontinuation of clinical development of bococizumab, a murine-derived, humanized antibody to proprotein convertase subtilisin–kexin type 9 (PCSK9), as now described ...

The research will look for potential human therapeutics based on the antibodies generated from VelocImmune mice against their research targets. Regeneron has an exclusive option to license the ...

The University of Georgia has been at the forefront of research utilizing transgenic mice. These genetically modified mice are valuable in studying human diseases due to their genetic similarity ...