Additionally, the authors highlight the influence of these techniques on organoid properties such as stemness, ...

Pancreatic cancer is projected to become the second-deadliest cancer by 2030. By the time it's diagnosed, it's often ...

A new study published in Life Science Alliance reveals a key genetic connection between cancer susceptibility and tissue ...

“We’re at the convergence of innovations and knowledge in cancer pathways and drug targets, organoid derivation, phenotypic high-throughput technologies and revolutionary analytics ...

Tangled spikes extended outward in all directions from a mass of mammary tumor cells until researchers treated them with a microRNA. This treatment set off a cascade of events that induced the cells ...

Maintenance and/or expansion of active PDX-derived organoids growing in Matrigel. PDO and PDXO-PDX derived tumor organoid culture. Generation of tumor organoid models from human patient or PDX tissue ...

We employ cutting edge patient-derived organoid and mouse models of colorectal cancer, transcriptomic, epigenomic and single cell approaches, and mechanistic studies to: (1) elucidate how tumor ...

Organoids have revolutionized science and medicine, providing platforms for disease modeling, drug testing, and understanding developmental processes. While not exact replicas of human organs, they ...

and brain tumor biology. This position offers an exciting opportunity to advance translational research using cutting-edge spatial transcriptomic and proteomic technologies, patient-derived organoid ...

Dr. Scott Magness will then present a case related to his group’s work investigating tumor cell heterogeneity through clonal organoid morphology and transcriptomics. He will discuss new approaches ...