Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

In repeat-associated diseases, the mutation would be 'THE CAT ATE THE ... The article, "A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo," was published ...

This genetic mutation is caused by the excessive production – or trinucleotide repeats – of cytosine, adenine, and guanine (CAG). These are three building blocks of DNA. Normally, CAG repeats ...

but the phenomenon has most notably been associated with a particular type of mutation, known as trinucleotide repeat expansions. However, other proposed explanations for this phenomenon include ...

They may also have an abnormal number of trinucleotide repeats in the CFTR gene on one chromosome and one severe mutation on the other. Because the symptoms of atypical CF are very similar to ...

Both types of myotonic dystrophy are caused by a mutation called a CTG (cytosine, thymine, guanine) trinucleotide repeat in the DMPK gene. This trinucleotide is repeated multiple times in a row.