Huntington’s disease arises from a genetic mutation that results in an abnormal expansion of the CAG trinucleotide sequence in the huntingtin (HTT) gene. This mutation causes the huntingtin ...
A small-molecule ligand that binds to a (CAG) n hairpin repeat is the basis of a biosensor to detect repeat length, which may help diagnose trinucleotide repeat disease severity. DNA trinucleotide ...
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