Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and ...

Unstable repeats are associated with various types of cancer and have been implicated in more than 40 neurodegenerative disorders. Trinucleotide repeats are located in non-coding and coding ...

which is why they are known also as trinucleotide repeat disorders," says one of the lead authors of the article, Ph.D. student Alex Sirp. Trinucleotide repeat disorders are a set of over 40 ...

Diseases associated with these mutations, including Huntington's disease, are called trinucleotide repeat disorders. Findings were published today in Nature Structural & Molecular Biology (http ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological disease.

John Brandsema, MD: There’s something that can sometimes happen in this group of disorders. It’s called the trinucleotide repeat disorder, and so what that means… Peter L. Salgo, MD ...

such as increased surveillance for the signs and symptoms of a particular disorder. Trinucleotide repeats are simple repetitive sequences of 3 nucleotides that follow the pattern of CNG ...

and other trinucleotide repeat disorders, because such changes in DNA occur naturally in people without disease or who only have mild symptoms. “Not only does this study show for the first time ...