The targeting of transport vesicles to the correct membrane destination involves a much larger set of proteins than anticipated and several layers of protein–protein interactions. The process of ...

Before Rothman's work on vesicles, this model had broad support. However, once scientists identified the large numbers of small transport vesicles surrounding the Golgi, researchers developed the ...

During the transport process, vesicles fuse with other intracellular organelles. However, observing this process is ...

Extracellular vesicles carry proteins and other molecules ... Singh predicted that EVs must have ion channels to safely transport molecules from cellular interiors to the extracellular environment ...

A major focus of research is on the COPII protein machinery responsible for synthesis of ER-derived transport vesicles. We are exploring the mechanisms utilized by COPII to segregate folded protein ...