A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the ...

is a state-of-the-art facility offering a wide range of services for the production and support of transgenic and gene-edited mouse and rat research models which are instrumental in understanding ...

APP 695 SWE mice expressing transgenic human APP with the two-point (Lys 670 →Asn, Met 671 →Leu) 'Swedish' mutation show age-dependent impairments in several histopathological features ...

Here we created an HBV transgenic severe combined immunodeficiency (SCID) mouse that consistently supports HBV gene expression and replication. After adoptive transfer of syngeneic, unprimed ...

Illustration of Transgenic Mouse Creation: This image shows the process of creating a transgenic mouse. A fertilized egg is held in place by a holding needle while an injection needle introduces ...

It turns out the human ear got off to a fishy start. Literally. A fascinating new study reveals that the mammalian outer ear has its evolutionary roots in the gills of ancient fish. This surprising ...

The team was able to detect, using DTI, the microstructural changes that characterise PanINs in pancreatic tissue samples and in vivo for transgenic mice that are prone to developing these lesions.

Our laboratory uses transgenic mice as a model system that can be engineered to reproduce focused aspects of the disease. These models allow us to test cellular and molecular hypotheses about causes ...

To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...