including medullary thymic epithelial cells and various dendritic cell subsets, express and present a diverse array of antigens and may select distinct repertoires of natural T Reg cells.

The adult thymus provides a variety of specialized microenvironments that support and direct T cell differentiation and selection. In this review, we summarize recent advances in the understanding ...

The thymus is a small, inconspicuous organ, but it is also vital for a functional immune system. This is because it is the development site of the T-lymphocytes (T-cells), which play a central ...

The thymus is one of the organs of the immune system where T lymphocytes develop, a type of cells that is essential to fight infections and prevent cancer. Without them, it's impossible to live.

They were able to reconstruct cell signals and movements. The researchers observed other cells in the thymus helping the T-cells to mature; the T-cells were given the chance to encounter many normal ...

to see if the organoids had the self-regulation capabilities of a real thymus, the scientists looked for markers of negative selection and T regulatory cell, or T reg, production. T regs are a ...

Its primary function involves T cell maturation. These cells help the body fight diseases, cancers, allergens, and more. The thymus also contains B cells. They help the thymus select the best T ...

More information: J. Luke Postoak et al, Thymic epithelial cells require lipid kinase Vps34 for CD4 but not CD8 T cell selection, Journal of Experimental Medicine (2022). DOI: 10.1084/jem.

A new study describes how the human thymus causes the list of friendly proteins that T cells should not attack. The research team identified, for the first time, the RNA molecules used to generate ...

The thymus sits in front of the heart and is where T cells mature; its age-related decline is associated with cancer, infections and autoimmune conditions, according to a Dec. 4 release about the ...

The thymus is a small, inconspicuous organ, but it is also vital for a functional immune system. This is because it is the development site of the T-lymphocytes (T-cells), which play a central ...