Cystic neoplasms of the pancreas may be more frequent than previously recognized ... The submucosal layer consists of a highly cellular stroma of spindle cells with elongated nuclei similar to the ...

The reason why pancreatic cancers are so difficult to treat is because of ‘stroma'. Stroma are microenvironments full of tissue and biological structures that shield the cancerous growth.

including mouse models of pancreatic cancer, three-dimensional cell culture systems such as patient-derived organoids, and diverse molecular- and cell-biological techniques enabling investigation of ...