The local stem cell environment (niche) is vital for stem cell maintenance and function in many tissues, and tenascin C in particular has been shown to play an important role within stem cell niches ...

Fritz Lipmann Institute (FLI) in Jena have discovered a previously unknown function of immune cells in the bone marrow.

Embryonic macrophages – specialized phagocytes of the immune system – influence the formation of blood stem cells and thus ...

Price also identified cells that lacked the myoblast marker myoblast determination protein 1 (MyoD) but expressed the satellite cell marker paired box 7 (Pax7). “What he found was that, in the niche ...

The maintenance of stem cells only within the niche explains the observation above that a genetically marked stem cell eventually stopped functioning as a stem cell. This can occur by chance if ...

Their micro-environment is often referred to as the stem cell niche. In different stem cell niches, surrounding cell groups and molecules influence what the stem cells will produce. The niche will ...

The stem cell niche Tissue stem cells are dependent on their surroundings and neighbour cells and in tissues they always work in cooperation with the stem cell niche. For example, intestinal stem ...

Every organ in our body contains a small number of adult stem cells that are specific to its niche. These cells act like a backup system. When needed, they divide to make copies of themselves or ...

Scientists at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena discovered a previously unknown function of immune cells in the ...