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Microbiome study finds bacteria in human gut rarely update their CRISPR defense systemsthat sequence produces a guide RNA that directs an enzyme called Cas9 to snip the viral DNA, preventing infection. These virus-specific sequences are called spacers, and a single bacterial cell ...
In addition, inhibition of Cas3-guided DNA degradation also blocks primed spacer acquisition. In summary, the AcrF3 dimer overcomes the CRISPR system at both the crRNA interference and the primed ...
Researchers develop optimized DNA hydrogels using minimized Takumi-shaped DNA nanostructures with potential biomedical applications.
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