Hosted on MSN1mon
Microbiome study finds bacteria in human gut rarely update their CRISPR defense systems
that sequence produces a guide RNA that directs an enzyme called Cas9 to snip the viral DNA, preventing infection. These virus-specific sequences are called spacers, and a single bacterial cell ...
News Medical on MSN2d
Scientists develop innovative DNA hydrogels for sustained drug release
Researchers develop optimized DNA hydrogels using minimized Takumi-shaped DNA nanostructures with potential biomedical applications.
Nature8y
A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
In addition, inhibition of Cas3-guided DNA degradation also blocks primed spacer acquisition. In summary, the AcrF3 dimer overcomes the CRISPR system at both the crRNA interference and the primed ...