Vascular proliferation contributes to the pathobiology ... In summary, the function of the intimal smooth muscle cell in the natural history of the atherosclerotic lesion seems to be to act ...

and promotes smooth muscle cell proliferation—factors that contribute to arterial narrowing. Given these mechanisms, targeting cuproptosis could open new avenues for AS treatment and prevention.

However, traditional metal stents may cause restenosis—a re-narrowing of the artery—due to excessive smooth muscle cell proliferation one month after implantation. Drug-eluting stents are ...

Keywords smooth muscle cell proliferation and plaque specific inflammation recombinant adenoviruses Areas of expertise I am involved in projects looking at the mechanisms that control smooth muscle ...