Our group is focused on understanding the role of endothelial and stem cells in heart and skeletal muscle diseases, metabolic regulation as well as in cancer. The major interest is in the endothelial ...

Insulin resistance is closely associated with obesity and is one of the earliest symptoms of type-2 diabetes. Endothelial cells are involved in the pathogenesis of insulin resistance through their ...

Several studies have also shown that vascular endothelial growth factor (VEGF ... We have isolated and thoroughly characterised a population of skeletal muscle-derived stem cells (MDSCs) that enhance ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling ... in glucose tolerance and enhanced insulin signaling in skeletal muscle and adipose tissue. Separate knockouts of ADM in adipocytes ...

Estrogen-related receptors (ERRs) regulate muscle mitochondria in mice, revealing a new potential drug targets for metabolic ...

Skeletal muscle heat shock protein 70 ... Fan M, Yang K, Wang X, et al. Endothelial cell HSPA12B and yes-associated protein cooperatively regulate angiogenesis following myocardial infarction. JCI ...

We hypothesise that potassium efflux from red cells and skeletal muscle causes hyperkalaemic death ... and through leucocyte-endothelial adhesion. Local inflammation amplifies endothelial activation ...

Research in the Leinwand lab focuses on unraveling mechanisms of genetic heart and skeletal muscle diseases using animal models, cell-culture systems and biophysical approaches. In addition to ...

Skeletal muscle is joined to bones. Its cells contract to make bones move and joints bend. Skeletal muscles always come in pairs, just like trainers. But there is a little bit more to it than that.