The idea of producing a medicine within insect cells destined for human use ... its suitability for AAV manufacturing. They infected Sf9 cell lines — derived from the fall armyworm — with ...

“The identification of the Sf-rhabdovirus in Sf9 cells was unexpected, since this cell line is used ... While rhabdoviruses are common in plants, Sf-rhabdovirus is the first known to infect the insect ...

Individual recombinant viral isolates are plucked from agarose and used to infect Sf9 insect cells. The infected Sf9 cells (for intracellular proteins) or culture supernatant (for secreted proteins) ...