Sertoli cell-only syndrome is a condition where the seminiferous tubules in the testes only hold Sertoli cells, “nurse” cells that assist in the production of sperm, causing infertility.

Testosterone, essential for spermatogenesis, is synthesized and secreted by the Leydig cells in response to stimulation by LH. FSH and testosterone act synergistically on Sertoli cells to promote ...

as accompanied by frequent vacuole formation starting at 32 dpt and the resultant “Sertoli cell-only syndrome”. These data indicate that Nat10 is essential for the maintenance of steady-state ...

In mice, the Cdc42 gene is necessary for the correct polarity of Sertoli cells that support sperm production, according to a new study. Findings may accelerate efforts to create a non-invasive ...