However, the large pool of vesicles in the cytoplasm derived from ... The organelles of the secretory pathway have been known for over 100 years, but explaining how they are constructed and ...

Upon activation, the actin network depolymerizes to allow for fusion of secretory vesicles with the plasma membrane for hormone release. Within the gonadotrope, LH and FSH are packaged into separate ...

However, it is not known which SNAREs are required for the fusion of secretory vesicles with the plasma membrane. To address this we have developed novel assays for measuring constitutive secretion ...