Newborn infants have little or no secretory IgA (SIgA) at birth. Earlier studies suggest that premature infants do not significantly differ from term babies in their rate of acquisition of SIgA.

Lactiga Inc. has been awarded a multiyear grant by the National Institute of Allergy and Infectious Diseases (NIAID) to accelerate the advancement of the company’s lead asset, LCTG-001.

This funding will accelerate the advancement of Lactiga’s lead asset, LCTG-001—the first-ever secretory IgA (sIgA) mucosally-targeted replacement therapy for patients with compromised immune ...

Reflecting maternal environmental exposition and in virtue of its multiple mechanism of action, secretory IgA in milk exerts a decisive role in direct and cross-protection against a variety of ...

Upper respiratory tract infection (URTI) is a common illness. Recent studies have shown that suppression of secretory immunoglobulin A (SIgA) is associated with increased incidence of URTI. Objective: ...

Extract: The production of IgG, IgA, IgM, β1c, and the secretory piece (SP) by the cells of human colostrum was investigated by radioimmunoelectrophoresis. The synthesis of IgA and β1c by the ...

Thus low concentrations of lymphocytes, suppressed natural immunity, suppressed lymphocyte proliferation, and suppressed levels of secretory IgA in saliva are found simultaneously with high levels of ...

[16] Breast milk contains high concentration of secretory antibodies, mainly IgA, with a broad range of specificities reflecting both maternal immunologic memory and antigenic stimulation of ...