pDCs are immune cells found in fibrotic skin but not in healthy skin and have previously been shown to contribute to scleroderma. In healthy cells, one X chromosome is typically deactivated, however, ...

Scleroderma is classified as a rare ... She has severe fatigue, arthralgias, and tight, itchy skin on her face, arms, hands, and trunk. She spends most of her days sitting up in the lounger ...

Skin changes on the fingers may be an aesthetic defect and a signal of a severe disease. Although scleroderma is rare, it is ...

"We show that CXCL4 prevents the normal termination of the immune response in the skin," explains Dr. Barrat. "Basically, the pDCs are attracted by the fibrosis, but instead of being suppressed as ...

Skin changes on the fingers may be an aesthetic defect and a signal of a severe disease. Although scleroderma is a rare ...

A new study validates the Scleroderma Skin Questionnaire (SSQ) as a reliable tool for assessing skin symptoms in systemic ...

Scleroderma is a rare disease in which a person's immune system begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result, connective tissue of the skin, lungs, ...

The actor, who died Sunday at age 65, was an "irreplaceable" part of the Scleroderma Research Foundation, says chairman Luke Evnin Julie Mazziotta is the Senior Sports Editor at PEOPLE ...

Find effective medications for 'Scleroderma treatment right here!' This page is a trusted source for both professionals and patients, detailing brand-name and generic options designed to manage ...

[2] Patients with diffuse cutaneous scleroderma with skin thickening on the proximal extremities or the trunk are in highest danger of developing SRC, at 20% to 25%, and so should be followed ...