The Sanger sequencing method is based on the incorporation ... producing a complex electropherogram with a colored peak representing each different nucleotide. Although all automated sequencers ...

Sanger sequencing has been the ... to the technologies involved, enabling the sequencing to be carried out in a faster, more automated manner; however, the core working principles remain the same. The ...

This Nature collection celebrates the 40th anniversary of the Sanger method for DNA sequencing, the most widely used sequencing method, pioneered by Fred Sanger and his team in 1977. In a Review ...

“There is significant debate within the diagnostics community regarding the necessity of confirming NGS variant calls by Sanger sequencing ... control guidelines regarding confirmatory sequencing ...