Streptozotocin (STZ)-induced diabetes in ICR mice is often used to model diabetes mellitus and its complications, as well as other pathologies. In studies of diabetes progression and effects of ...

To further understand the characteristics of de- and trans-differentiation of islet cells, the team performed scRNA-seq of mouse islets in STZ-induced diabetes. ScRNA-seq confirmed the dynamic ...

In a streptozotocin (STZ) mouse type 1 diabetes model, analysis of 12,000 genes screened showed that expression of 513 genes increased or decreased significantly in uncontrolled diabetic animals.

Genprex, Inc. ("Genprex" or the "Company") (NASDAQ: GNPX), a clinical-stage gene therapy company focused on developing ...

The drug candidate SRI-37330 is a non-toxic small molecule that effectively rescued mice from streptozotocin- and obesity-induced diabetes and improved glucose homeostasis. A study published in ...

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling ...

Christof Westenfelder, MD, founder and CEO of SCT, stated, "We continue to advance our durable cure for those suffering from Type 1 Diabetes ... in STZ-diabetic NOD/SCID mice adds further support ...

The drug candidate SRI-37330 is a non-toxic small molecule that effectively rescued mice from streptozotocin- and obesity-induced diabetes and improved glucose homeostasis. A study published in the ...

The drug candidate SRI-37330 is a non-toxic small molecule that effectively rescued mice from streptozotocin- and obesity-induced diabetes and improved glucose homeostasis. A study published in the ...

The drug candidate SRI-37330 is a non-toxic small molecule that effectively rescued mice from streptozotocin- and obesity-induced diabetes and improved glucose homeostasis. A study published in the ...