A normal mouse (left) stays for 2 minutes. The MLIV mouse has impaired motor skills.

Mice administered 2% glucose showed comparable numbers of ubiquitin-positive aggregates in motor cortex and striatum and comparable rotarod performance to untreated mice (Figure 5c-e).

They injected either antibody into the mouse peritoneum weekly for 14 weeks. At that point, mice given RNJ1 or HJ8.5 had 12 or 8.5 percent less total tau in whole brain lysates, respectively, than did ...

A team at Johns Hopkins University and the Howard Hughes Medical Institute compared eye-movement analysis with the commonly used rotarod test of motor coordination in mice treated with a number of ...

The dbl-PAC-Tg(SNCA A53T) +/+;Snca-/-model, referred to here as double-transgenic mice, are mice lacking endogenous α-synuclein (Snca knockout mice) that were crossed with two homozygous transgenic ...