Approximately 30% of the nucleolar proteome consists of proteins involved in ribosome biogenesis, marking the nucleolus as the central location for ribosome assembly (Boisvert et al., 2007).

"The nucleolus is perceived as a basic housekeeper: It's responsible for producing ribosomal RNA ... enlarged nucleoli with increased ribosome biogenesis. It is still unclear why a small nucleolus ...

to produce and assemble mature ribosomal proteins (rRNAs) Most ribosome biogenesis occurs in the nucleolus, beginning with the transcription of 47S pre-rRNA from ribosomal DNA loci by the enzyme ...

The nucleolus is a special part of the cell nucleus that houses ribosomal DNA ... are affecting ribosome biogenesis and to what degree," said Potapova. "Hitting ribosome biogenesis could be ...

Curiously, when the researchers truncated poly-GR from 149 repeats to 53, it behaved more like the 175-mer polyPR, moving into the nucleolus, knocking down ribosomal biogenesis and protein translation ...

researchers showed that incorporation within the nucleolus required NPM1 binding with both nucleolar proteins that include the arginine-rich segments and ribosomal RNA. The researchers also ...

The nucleus holds the cell's chromosomes and the nucleolus where the ribosomal DNA (rDNA) is housed. The nucleolus isolates the rDNA which encodes the RNA portions of the ribosomes, the protein ...

Some RNAs were present at higher-than-normal concentrations. Kwon also used polymerase chain reaction to examine the production of ribosomal RNA. Normally, the nucleolus processes the 45S rRNA ...

Recent work by scientists at the University of Texas MD Anderson Cancer Center in Houston shows that during cell-growth inhibition, ribosomal protein L11 translocates from the nucleolus to the ...

The yellow cells, indicated by arrows, are the first evidence of increased ribosome biogenesis in cells during epithelial-to-mesenchymal transition (EMT). [Vincent et al.] Researchers from Uppsala ...