The Pre-Initiation Complex (PIC), which consists of Mediator, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (RNAPII), governs the expression of all protein-coding and most non-coding ...

Nature Reviews Molecular Cell Biology - In vivoanalysis of RNAPII elongation shows that splicing does not alter elongation rates. Skip to main content. Thank you for visiting nature.com.

The transcription factor HIF1A is a key mediator of the cellular response to hypoxia. Despite the importance of HIF1A in homeostasis and various pathologies, little is known about how it regulates RNA ...

Maeshima and colleagues propose that hubs of RNAPII and other components of the gene transcription machinery constrain chromatin movements by connecting different chromatin regions together into ...

We discovered that CDK9-mediated, RNAPII-driven transcription is functionally opposed by a protein phosphatase 2A (PP2A) complex that is recruited to transcription sites by the Integrator complex ...

RNAPII signals on histone genes also correlated with clinical grades in meningiomas, accurately predicting rapid recurrence as well as the tendency of whole-arm chromosome losses.

In their study, the Stanford researchers also discovered a supplemental mechanism that kicks in when cells get too big and there simply isn’t enough RNAPII to go around. Somehow, the stability of mRNA ...

RNAPII signals on histone genes also correlated with clinical grades in meningiomas, accurately predicting rapid recurrence as well as the tendency of whole-arm chromosome losses.

RNAPII signals on histone genes also correlated with clinical grades in meningiomas, accurately predicting rapid recurrence as well as the tendency of whole-arm chromosome losses. Using this ...

Change in RNAPII Protein Structure Guides Production of RNA from DNA. by Bidita Debnath on November 10, 2013 at 11:04 PM. Transcription is one of biology's most fundamental processes.