Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double strand break can result in insertion or deletion mutations, while repair pathways can be ...
Efficient RNA interference in Caenorhabditis elegans ... or more processive RdRP activity coupled with a specific endonuclease or exonuclease that cuts or trims the secondary siRNA to 22 or ...
Richards first encountered endonuclease R during his postdoctoral fellowship at ... Roberts originally intended to focus on using restriction enzymes to sequence DNA, echoing the RNA sequencing ...
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