Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease of lung parenchymal scarring that is triggered by ...

Lung epithelial cells are increasingly recognized to be active effectors of microbial defense, contributing to both innate and adaptive immune function in the lower respiratory tract. As immune ...

In animal models, inhibition of neutrophil chemokines or disruption of these chemokine gradients in the lung attenuates ALI. Molecules associated with enhanced wound closure, such as epithelial ...

Arlen et al, Cannabis vaping elicits transcriptomic and metabolomic changes involved in inflammatory, oxidative stress, and cancer pathways in human bronchial epithelial cells, American Journal of ...

resulting in progressive pulmonary function deterioration. In particular, the surface of the alveoli (called the alveolar epithelium) is often affected. If the disease's origin is unknown ...

“Epithelial cells in the lung are typically envisioned as supporting respiratory functions, while MHC-II is understood to connect immune cells to immune cells, so the finding that MHC-II on lung ...

The formation of a chimeric lung was confirmed by detection of human transcripts for epithelial and vascular genes. In addition, the self-renewal and long-term proliferation of human lung stem ...

Lung (pulmonary) sarcoma is a rare type of lung cancer. Most lung cancers start in epithelial cells that line your airways, but pulmonary sarcoma develops in connective tissue or other ...

Attempts to understand the complex pathobiology of the mediators of ALI have led to improvements in clinical outcomes, particularly in terms of low tidal volume ventilation. [53] Ventilation with ...

resulting in progressive pulmonary function deterioration. In particular, the surface of the alveoli (called the alveolar epithelium) is often affected. If the disease's origin is unknown ...