This article reviews the published literature on the use of venlafaxine, fluoxetine, and paroxetine for the treatment of hot flashes.

“As the definitive physiology of hot flashes is not known, I believe it cannot be assumed that the efficacy of the new antidepressants for hot flashes is a class effect,” says lead researcher ...

The analysis by Loprinzi and co-workers supports the notion that antidepressants and gabapentin decrease menopausal hot flashes. In addition, the study showed that venlafaxine and paroxetine were ...