But rather than the scavengers and microbial decomposers at work in macroscale habitats, much of the protein recycling work within the cell falls to a barrel-shaped protein complex known as the ...

Cells maintain a continuous free pool of ubiquitin that can be conjugated onto target proteins to mark them for degradation by the proteasome. Now, in Cell, Finley and colleagues show that the ...

Reporting in Nature, Lin and colleagues show that selective inhibition of the mycobacterial proteasome with certain oxathiazol-2-one compounds might be useful in targeting this non-replicating ...

Dr. Park's laboratory studies the biogenesis of a molecular machine known as the proteasome, a major protease in eukaryotes. Her studies have changed the traditional view of the spontaneous formation ...