healthy volunteers were given two 12.5-mg promethazine rectal suppositories, one 25-mg suppository, one 50-mg suppository, or 50 mg (10 mL) of promethazine oral syrup. Blood samples were collected ...

Thirty-seven subjects were enrolled, and 36 of them completed the study. After enrollment and completion of study period 1 (treatment D, 50 mg [10 mL] of promethazine oral syrup), one subject was ...