This has an enormous impact on the mortality and morbidity resulting from malaria infection, especially in sub-Saharan Africa, where the lethal human parasite species Plasmodium falciparum ...

So far, no preventative vaccination against malaria exists, and its control depends heavily upon antimalarial drugs that ... mutations within P. falciparum that conferred resistance to CQ arose ...

I t’s not clear why, but the Greater Mekong Subregion—Cambodia, southern China, Laos, Myanmar, Thailand, and Vietnam—is a major source of malaria drug resistance. Each time a drug has been deployed in ...

The development of resistance to currently used antimalarial drugs necessitates continuing efforts to develop new drugs, ideally with novel modes of action against both the liver and blood stages ...

We suggest that future combinations of antimalarial drugs should have similar pharmacokinetics to delay the development of resistance ... associated with Plasmodium falciparum plasmepsin 3 ...

In 2022, nearly 619,000 global deaths due to malaria were caused by Plasmodium falciparum ... For decades, the parasite's resistance to all antimalarial drugs has posed a big challenge for ...

Treatment failure for Plasmodium falciparum ... drugs, treatment failure, and criteria for outpatient treatment. The discussion also reviewed the role of molecular surveillance in identifying ...

According to Professor Rachel Cerdan of the University of Montpellier, the big concern is the resistance of the parasite, Plasmodium falciparum, to antimalarial drugs. "It's something that ...

Plasmodium parasites that cause Malaria infect hundreds of millions each year, but we still lack a full understanding of how they transmit from host to host and the conditions that enable Plasmodium ...