This is the first study to identify and develop small molecules—termed "molecular glues"—that enhance the interaction between ...

More information: Francesca Chandler et al, Molecular glues that inhibit deubiquitylase activity and inflammatory signaling, Nature Structural & Molecular Biology (2025). DOI: 10.1038/s41594-025 ...

Molecular glues have emerged as one of the promising approaches for drug discovery to treat a wide range of diseases such as cancer, inflammatory and immune diseases, and infections. Currently, ...

Could it be that one of only three known markers directly targeting the DNA does not exist outside the realm of microbes? Now ...

Ben Hargreaves investigates why molecular glues are seeing greater levels of investment, and how they could provide treatments for a broad range of conditions. Molecular glues are types of ...

Pennsylvania-based SEED Therapeutics has leveraged the unmatched expertise of its founding team to develop a target-first molecular glue discovery platform. A series of discoveries in recent ...

We have excellent teaching, research, and outreach programs in the areas of plant biology (cellular, genetics, genomics, microbial, molecular and physiology), agronomy (including pathology, soil ...