To understand how Bil works, Sorek’s team compared phage progeny from infected bacteria with and without the system. They performed density gradient centrifugation to separate phages from bacterial ...

In this way, scientists could retain only positive clones and immediately use their selected phage to generate more phages. This made screening higher throughput, as researchers could screen thousands ...

Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

Bacteriophages, the most abundant life form on Earth, infect bacterial cells and influence the structure of the microbial ...

Because phages exert pressure on the bacteria they infect and some phage genomes encode virulence factors and toxins, a role for specific phages or communities of phages in human health seems ...

The Phage Genomics Lab courses ,sponsored by the HHMI Science Education Alliance, offers introductory biology students an authentic research experience. Students isolate novel bacteriophage from the ...

Their potential as antibacterial agents was appreciated almost immediately, with the first 'phage therapy' trials predating Fleming's discovery of penicillin by approximately a decade. In this ...