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New marker identifies the functional maturity and heterogeneity of stem cell–derived islet organoids
Over 500 million people worldwide suffer from diabetes-a disease that contributes to major complications such as stroke, ...
The pancreas is a ... the exocrine acini, which produce and secrete enzymes for the breakdown of lipids, proteins and carbohydrates, and the endocrine islets of Langerhans, which release various ...
the acini and ducts of the exocrine pancreas and the endocrine islets of Langerhans. Acinar cells release enzymes that help break down food, while ductal cells form channels to carry the enzymes ...
Replacing faulty or missing cells with new insulin-making cells has been the object of diabetes research for the last decade. Past studies in tissue culture have suggested that one type of ...
Model more closely replicates natural environment of the pancreas, which will be essential for studying diabetes and ...
In an effort to reduce the ratio of presumably noncontributing acinar tissue to islet tissue specimens were obtained that demonstrated atrophy of the pancreatic acini in dogs two months after ...
Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance, published in ...
A group of more than 50 experts in the field of pancreatic islet cell transplantation is calling for reclassification of the type 1 diabetes therapy from biologic drug to human organ. The ...
The use of pancreatic islets (hormone-producing cells) is increasing in diabetes research and may play an important role in future treatments, according to an article in the April 15 issue of JAMA ...
Representative bioluminescence (left), fluorescence (centre) and axial MR images (right) of 3000 and 1000 pancreatic islets transplanted into scaffolds, on days 4 and 14. (Courtesy: A. Gálisová et al.
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