Osteoclasts are cells in the body that play a role in breaking down old bone tissue. Osteoblasts then play a role in the formation of new bone tissue. Multiple myeloma can upset the balance of ...

The imbalance occurs between osteoblasts, responsible for bone formation, and osteoclasts, which break down bone tissue. This ...

The imbalance occurs between osteoblasts, responsible for bone formation, and osteoclasts, which break down bone tissue. This disrupted process results in weakened bones and increased ...

Reducing circulating estrogen levels increases osteoclast activity and, therefore, bone loss. 9 Not only is the balance of osteoblasts and osteoclasts altered, but the microenvironment of the ...

Osteoblasts act in a group ... life to maintain bone architecture balance and systemic mineral homeostasis. During this "remodeling" process, osteoclasts remove mineralized bones, whereas ...

Bone mass and strength are maintained by the bone remodeling cycle involving the integrated actions of osteocytes, osteoclasts and osteoblasts. Current therapies for the prevention and treatment ...

“Bone is a highly active organ, undergoing continuous osteoblast-induced bone formation and osteoclast-mediated bone resorption throughout life,” the authors explained. “The process of bone ...