Selective transport through the nuclear pore complex presents a very complicated case—a lot of ins, a lot of outs, a lot of what-have-yous. To have any hope of unraveling the case, scientists ...

The nuclear pore is a protein-lined channel in the nuclear envelope that regulates the transportation of molecules between the nucleus and the cytoplasm. In eukaryotic cells, the nucleus is ...

Researchers reveal that Merkel cell polyomavirus bypasses normal nuclear entry routes by exploiting the temporary breakdown ...

such as the pores in the nuclear envelope. However, this process is normally slow and can take up to one minute to capture an image. In comparison, modern high-speed AFMs are able to record movies ...

Nuclear pores are essential elements of all cells ... many nuclear transport channels are assembled into a given nuclear envelope remain unclear. Here, we report that depletion of the NPC basket ...

Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into and out of the nucleus. This microscopic metropolis relies on an ...

La Jolla, CA – Researchers have long wondered how nuclear pores – the all-important channels that control the flow of information in and out of a cell's nucleus – double in number to prepare ...

Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a ...

The nuclear envelope, for example, is a highly regulated membrane barrier ... rupture because they are not able to diffuse back to the cytosol through the nuclear pores following nuclear membrane ...

Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a membrane ...