Selective transport through the nuclear pore complex presents a very complicated case—a lot of ins, a lot of outs, a lot of what-have-yous. To have any hope of unraveling the case, scientists ...

The nuclear pore is a protein-lined channel in the nuclear envelope that regulates the transportation of molecules between the nucleus and the cytoplasm. In eukaryotic cells, the nucleus is ...

La Jolla, CA – Researchers have long wondered how nuclear pores – the all-important channels that control the flow of information in and out of a cell's nucleus – double in number to prepare ...

Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into and out of the nucleus. This microscopic metropolis relies on an ...

Nuclear pores are essential elements of all cells ... many nuclear transport channels are assembled into a given nuclear envelope remain unclear. Here, we report that depletion of the NPC basket ...

Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a ...

Nuclear pore complex outer rings: No longer 'one size fits all' Date: June 12, 2019 Source: Osaka University Summary: In eukaryotic cells, molecules can only move into or out of the nucleus ...

Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a membrane ...

The nuclear envelope, for example, is a highly regulated membrane barrier ... rupture because they are not able to diffuse back to the cytosol through the nuclear pores following nuclear membrane ...

Researchers at Kanazawa University report in Cell Reports how alterations in the nuclear pores lead to the degradation of anti-tumor proteins. Several types of cancer are believed to be linked to ...