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Nature Biotechnology is a monthly journal covering the science and business of biotechnology. It publishes new concepts in technology/methodology of relevance to the biological, biomedical ...

Many universities and institutions have open access funding agreements with Springer Nature. Find out if your institution has an agreement that can cover the article processing charge (APC) when ...

A model of two zinc-finger nucleases bound to DNA overlaid on an image of a metaphase chromosome spread. The side chains shown are key to the dimer interface of the cleavage domains, according to ...

Similar to outsourcing in the corporate world, technology incubators are beginning to look beyond their own borders to find technology.

In this issue, several groups report their findings on the development of methods to detect SARS-CoV-2 in patients and in the community, and benchmark assays to detect SARS-CoV-2-specific antibodies.

Reconstruction of nerve bundles in a rhesus monkey brain. Fang Xu et al. present a method to image a whole monkey brain at micrometer resolution in 100 hours. See Xu et al. Image: Chao-Yu Yang and ...

Protein language models learn from diverse sequences spanning the evolutionary tree and have proven to be powerful tools for sequence design, variant effect prediction and structure prediction.

Optimizing guide RNA design for Cas13. With data from massively parallel screens, Wessels et al. develop computational models to identify optimal guide RNAs for the RNA-targeting CRISPR enzyme Cas13d.

Aedes aegytpi mosquitoes are imaged in a sex-sorting device. Crawford et al. describe the production of accurately sorted sterile male mosquitoes and their deployment in a mosquito-eradication trial.

Scanning electron micrograph of a heart-forming organoid showing a myocardial layer (pink) separated by a thin endocardial layer (blue) from an anterior foregut endoderm and vascular layer ...

The painting Histone Subunit Exchange portrays the dynamic nature of nucleosome structure. This issue focuses on the role of epigenetics in health and disease and discusses the therapeutic ...