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Nature Biotechnology is a monthly journal covering the science and business of biotechnology. It publishes new concepts in technology/methodology of relevance to the biological, biomedical ...

A model of two zinc-finger nucleases bound to DNA overlaid on an image of a metaphase chromosome spread. The side chains shown are key to the dimer interface of the cleavage domains, according to ...

Similar to outsourcing in the corporate world, technology incubators are beginning to look beyond their own borders to find technology.

In this issue, several groups report their findings on the development of methods to detect SARS-CoV-2 in patients and in the community, and benchmark assays to detect SARS-CoV-2-specific antibodies.

Reconstruction of nerve bundles in a rhesus monkey brain. Fang Xu et al. present a method to image a whole monkey brain at micrometer resolution in 100 hours. See Xu et al. Image: Chao-Yu Yang and ...

Optimizing guide RNA design for Cas13. With data from massively parallel screens, Wessels et al. develop computational models to identify optimal guide RNAs for the RNA-targeting CRISPR enzyme Cas13d.

Scanning electron micrograph of a heart-forming organoid showing a myocardial layer (pink) separated by a thin endocardial layer (blue) from an anterior foregut endoderm and vascular layer ...

Drug pipeline 3Q23 — ERT, bispecifics and CRISPR in sickle cell disease John Hodgson Data Page 10 Nov 2023 3Q23 — VCs feed ‘older children’ as IPO markets stagnate John Hodgson ...

The scarcity of organs for transplantation could be addressed in part by extending viable preservation time of retrieved organs. Using an ice-free supercooling approach, Uygun and colleagues ...

Insect pests such as the cotton bollworm Helicoverpa armigera consume a substantial portion of global agricultural outputs. Mao et al. (p 1307) and Baum et al. (p 1322) show that ingestion of ...