From mouse to patient The xenogeneic GvHD model in NSG™ mice provides the unique opportunity to test therapeutic approaches in an in vivo scenario. There are several advantages of using a mouse ...

Scientists have created mice with a hormone profile that causes growth and metastatic spread of implanted human breast tumors. Results show that the team created a new mouse breed, called NSG-Pro ...

NSG™ Mice Reveal the Effect of CAR T Therapy In a recent study by Zhou and colleagues, the authors examined the impact of a modified CAR T therapy on NSG™ mice from JAX, injected with a TNBC ...

By 16 weeks post engraftment, approximately 50% of humanized NSG™-SGM3 mice are expected to succumb to anemia, whereas huNOG-EXL viability remains >90%.

This new mouse model, called NSG-Pro, supports greatly enhanced growth of implanted ER-positive human breast cancers.

A new study published in Microbiology Spectrum reports the establishment of a liver-humanized NSG-PiZ mouse model that is fully permissive to hepatitis B virus (HBV) infection. In this model, HBV can ...

B6/HLA-A2 mice were injected with 8F4 (10 mg/kg) three times weekly for a total of 10 injections, the dosing schedule in which 8F4 showed effective elimination of established AML in NSG treatment ...

More information: Sadaf Hasan et al, Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice, Protein & Cell (2024). DOI: 10.1093/procel/pwae014 ...

This new mouse model, called NSG-Pro, supports greatly enhanced growth of implanted ER-positive human breast cancers.

In this webinar, Dr. Elinor Willis will cover the characterization of myeloid cell hyperactivation syndrome in CD34+ HSC-humanized NSG-SGM3 and NOG-EXL mice, including significant new histopathology ...