JAX, with over 11,000 strains, enables access to cutting-edge, humanized-PBMC-NSG™- mice—one of the most widely used models to study human-to-mouse-xenogeneic GvHD, as well as immune function ...

By 16 weeks post engraftment, approximately 50% of humanized NSG™-SGM3 mice are expected to succumb to anemia, whereas huNOG-EXL viability remains >90%.

NSG-Pro mouse model for uncovering resistance mechanisms and unique vulnerabilities in human luminal breast cancers. Science Advances , 2021; 7 (38) DOI: 10.1126/sciadv.abc8145 Cite This Page : ...

In a recently published study by Zhou and colleagues used NSG™ mice from JAX to test CAR T therapy in TNBCtumor (Zhou et al., 2019). NSG™ Mice Reveal the Effect of CAR T Therapy.

Super immunodeficient mice such as the NOG-EXL and NSG-SGM3 combine severe immunodeficiency with transgenic expression of human myeloid-stimulatory cytokines. These mouse strains support an improved ...

"The NSG-Pro mouse model provides previously inaccessible precision medicine approaches for ER-positive human breast cancers," said Yunguang Sun, MD, PhD, joint lead author of the study and ...

A new study published in Microbiology Spectrum reports the establishment of a liver-humanized NSG-PiZ mouse model that is fully permissive to hepatitis B virus (HBV) infection. In this model, HBV can ...

Among the more than 4,000 mouse mutant strains that the Jackson Lab maintains and distributes to the worldwide academic community is a mouse similar to NOG, called NSG.