Solution state NMR will also have a complementary role in post-genomic analysis, particularly considering that (i) many protein targets do not provide crystals suitable for crystallographic analys ...

NMR has become a valuable screening tool for analysing the binding of ligands to protein targets. Furthermore, NMR can provide structural information on protein–ligand interactions to aid in the ...

This binding is essential, so we used NMR to map the interaction of this dengue virus capsid protein with these lipid droplets. Since the binding is essential, we know that this could shed light ...

In LC8-IDP duplex scaffolds, some disordered regions form higher order structure, and we can identify those regions by NMR. One LC8 partner is dynein intermediate chain (IC), a protein from the ...

NMR Spectroscopy Proving Value as Supplement to X-Ray Chrystallography Not so long ago, structural proteomics research was divided into two distinct campsx-ray crystallography and NMR spectroscopy.

Researchers have revealed the mechanism underlying GPCR function using a GPS nuclear magnetic resonance (NMR) technique.

One technique, called magic-angle spinning nuclear magnetic resonance, or MAS-NMR, has proven highly successful as a way of determining the properties of complex molecules such as some proteins. But ...

They successfully obtained several diagnostic parameters from a single, short, NMR experiment. In addition to genomics and proteomics, metabolomics is becoming established as another mainstay of ...

But NMR analysis of protein folding has typically involved one-shot methods that can’t easily achieve high time resolution. The challenge was finding a way to rapidly and repeatedly impose and ...

This is much longer than traditional NMR, which can only detect motion on nanosecond timescales — not long enough to get a good look at all of the possible shapes the protein can adopt, according to ...

A study by researchers at the Interuniversity Institute of Bioinformatics in Brussels, the Structural Biology research group ...

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University of ...