Immunofluorescence image of mouse liver 72 hours after acetaminophen administration. TP53INP1 (green) marks a distinct population of cells emerging around necrotic areas. This image highlights the ...

Immunofluorescence image of mouse liver 72 hours after acetaminophen administration. TP53INP1 (green) marks a distinct population of cells emerging around necrotic areas. This image highlights the ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

The level of LacZ gene expression in the internal organs including the lung, heart, liver, spleen and kidney was determined by X-gal staining method.35 Tissue sections (10 μm thickness) were made ...

How do you study-and try to cure in the laboratory-an infection that only humans can get? A team led by Salk Institute researchers does it by generating a mouse with an almost completely human liver.

More information: Zachary Dewald et al, Altered drug metabolism and increased susceptibility to fatty liver disease in a mouse model of myotonic dystrophy, Nature Communications (2024). DOI: 10. ...

“In the same liver, the human liver cells were filled with fat, a typical characteristic of the human disease, while the mouse liver cells remained normal.” Next, the researchers analyzed the products ...

Mouse and human cells talk in different languages, but we have enabled human liver cells to speak in their own language within living mice Professor Richard Flavell, Yale School of Medicine ...

Mouse with human liver: New model for treatment of liver disease. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2010 / 02 / 100222182144.htm ...

Altered drug metabolism and increased susceptibility to fatty liver disease in a mouse model of myotonic dystrophy. Nature Communications, 2024; 15 (1) DOI: 10.1038/s41467-024-53378-z; ...