Monoclonal antibody therapy is complicated by the potential for the human immune system to form antibodies to these drugs. Antibodies can be formed to the Fv and Fc regions or to murine epitopes.

Better diagnostics, more focused treatment, and deeper understanding of individualized symptoms could all take major steps ...

aggressive hyperinflammatory condition—who were treated with the first-in-class monoclonal antibody, ELA026, experienced a 100% response rate and an improved survival rate at two months ...

Sanofi and Regeneron's fully human monoclonal antibody Dupixent (dupilumab) has gained approval from the US Food and Drug ...

FDA grants orphan drug designation to HLX22 for gastric cancer, with a phase 2 trial showing improved progression-free survival and objective response.

“Similarly, there is an unmet medical need for treatment, a need which IgGenix is hoping to address.” IgE, which is a specific class of monoclonal antibody, triggers reactions after people are ...

The company became practically a household name when its monoclonal antibody COVID-19 therapy REGEN-COV2 was used to treat President Donald Trump in 2020 during his first presidential term.

TG Therapeutics (TGTX) announced the publication of two journal articles one describing the evolution of CD20 treatments for multiple sclerosis ...

Title: Switching to Ublituximab from Prior anti-CD20 Monoclonal Antibody Therapy: A Case Report Series The article describes a retrospective case series of seven individuals with multiple ...