Mitochondrial dynamics protein 49 kD (M:D49) and mitochondrial dynamics protein 51 kD (M:D51), which are located in the mitochondrial outer membranes, form division-inducing rings around mitochondria.

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately ...

Mitochondria have a fundamental role in regulating metabolic pathways, and tight control of mitochondrial functions and dynamics is critical to maintaining adequate energy balance. In complex ...

This fundamental study combines in vitro reconstitution experiments and molecular dynamics simulations to elucidate how membrane lipids are transported from the outer to the inner membrane of ...

The fusion of two or more mitochondria, and the fission of a mitochondrion into two units are common phenomena known as "mitochondrial dynamics" and both processes are necessary for the proper ...

Now, collaborative research co-led by Dr. Julie St-Pierre's lab at the Faculty of Medicine sheds new light on the mysteries of mitochondrial dynamics and its likely role in the metastatic progress ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 ...

The central goal of research in the Mears Lab is to investigate proteins that regulate mitochondrial dynamics. Mitochondrial dynamics has recently come to the forefront as a therapeutic target in ...

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Intermittent fasting in humans may increase mitochondrial dynamics and thus increase lifespan, Singh said, adding this idea still requires more research. Future research in this avenue may lead to ...

Mitochondrial function is critical to health, and disruption of mitochondrial dynamics the cycle of repairing dysfunctional mitochondria and restoring the connectivity among the energy-producing ...