Mitochondrial DNA can be subdivided into various classes—termed haplogroups—on the basis of its pattern of single nucleotide polymorphisms. Several small, and as yet unreplicated, studies have ...

Purpose It has been hypothesised that certain mitochondrial haplogroups, which are defined by the presence of a characteristic cluster of tightly linked mitochondrial DNA polymorphisms, would be ...

There are approximately 25 to 35 basic mitochondrial DNA haplogroups. To investigate the impact of mitochondrial DNA, Ballinger and his colleagues looked for changes in metabolism and nuclear gene ...

People interested in their genetic composition can learn about their DNA structure. The DNA molecule is a fundamental substance throughout human bodies, plants, plant organisms, and all microorganisms ...

Mitochondrial DNA haplogroups revealed substantial African matrilineal influence, with nearly one-third of Yemeni samples carrying African-specific mtDNA haplogroups such as L2a1, the most ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt cellular energy production. Researchers have identified a molecule that helps ...

What happens to your cells when this DNA mutates? Similar to the nuclear genome, the mitochondrial genome is built of double-stranded DNA, and it encodes genes (Figure 2). However, the ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt ...

Notably, two individuals in haplogroup H1bu exhibited similar but not identical profiles, both sharing a point heteroplasmy—where multiple copies of mitochondrial DNA (mtDNA) differ at a specific ...