Mitochondrial diseases affect approximately 1 in 5,000 people ... targeted platinum transcription activator-like effector nucleases (mpTALENs)—specialized enzymes that can selectively target and ...

The human body undergoes numerous changes throughout life, with many significant transitions occurring during the decade of ...

How well our brain functions depends heavily on the performance of our nerve cells. That is why they are regularly checked for their proper function -- defective cell components are marked, disposed ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 Diabetes, ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in ...

Mitochondrial DNA must also be repaired after factors like oxidative stress damage it. However, around 300 different mutations in the POLG gene derail this replication-and-repair process by messing ...

The study, titled "Deubiquitinating Enzymes Regulate Skeletal Muscle Mitochondrial Quality Control and Insulin Sensitivity in Patients with Type 2 Diabetes," was recently published in the Journal ...