But another study has shown that p16 cells help mice heal cuts on their skin. However, the role of p21 cells in wound healing is largely unknown. Xu's lab took young adult mice with a cut in the ...

we subjected p21 knockout (p21-/-) mice to repetitive inhalations of lipopolysaccharide (LPS), an exposure that leads to chronic bronchitis and accumulation of senescent cells," write the researchers.