Negative selection in fetal thymus clonally deletes many self-reactive T cells, permanently removing ... factor regulating genes implicated in Treg development was confirmed.

The thymus is a crucial training ground for T-cells, the body's "white knights," where they learn to battle the various diseases they may encounter. Thymic function shrinks to nearly nothing as we age ...

called the thymus. While it might not be as well-known as other organs, its function is vital: it's a key component of our immune system, responsible for the maturation of T-cells, which protect ...

Data now show that thymus-derived self-peptide-specific ... sites for B7H3 cell surface localization and T cell inhibition, followed by the development of N91/309 and N104/322 preferentially ...

He uses mouse models to study the thymus, the organ in which specialized immune cells called T cells mature. His goal is to apply his findings to develop new therapies to promote immunity in cancer ...

The study, "Regulatory T Cell Epitope Content in Human Antibodies Decreases During Maturation", was conducted by Andres Gutierrez, PhD and Annie De Groot, MD of EpiVax, using existing antibody ...